Description
Linagliptin works by inhibiting dipeptidyl peptidase 4 (DPP-4) which inactivates the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, thus prolonging incretin activity in response to ingestion of food. This increases insulin sensitivity, decreases glucagon secretion and improves pancreatic beta cell function.
Inform the physician if the patient is allergic to the active ingredients and any other drugs. Brief about the allergy and the signs like:
• Rash
• Itching
• Shortness of breath
• Swelling of face, lips, tongue or throat or any other signs.
The patient should tell the doctor about any history of:
• Pancreatitis
• Kidney or hepatic disease
• Diabetic ketoacidosis
